Fastest Method: Run your own node and link to it locally http://127.0.0.1
Next fastest method: Use a Node closest to your location
http://za.globalsafex.com - Africa
http://au.globalsafex.com - Australia
http://cn.globalsafex.com - China
http://eu.globalsafex.com - Europe
http://uk.globalsafex.com - London
http://na.globalsafex.com - North America
http://sa.globalsafex.com - South America
Least fasted Method: Use a centralized node that has varying levels of traffic: http://rpc.safex.org